The Prime®


ProGIGuard is a breakthrough in gastrointestinal pain management.

Study Results
A randomized double-blind placebo-controlled study with Saccharomyces cerevisiae CNCM I-3856, 500mg per day for 8 weeks, was carried out on 200 volunteers with IBS.
  • After the 2nd week of consumption, subjects felt a significant reduction in abdominal pain (significant difference between placebo and active product).
  • 63% of subjects experienced an improvement in their pain/discomfort score during the 2nd month of consumption (significant difference between placebo and active product).
  • CNCM I-3856 also showed a rebalancing effect of the intestinal microflora.
Multi-centric randomized double-blind placebo-controlled study on the effect of Saccharomyces cerevisiae CNCM I-3856, 1,000 mg per day for 12 weeks, was carried out on 379 volunteers with IBS-C.
  • Subjects consuming CNCM I-3856 felt a significant easing of their abdominal pain and discomfort from the 1st week onwards (significant difference between placebo and active product).
  • They also felt significantly improvement in all symptoms (abdominal/intestinal pain and discomfort, bloating, flatulence and constipation).
A large consumer study (1160 participants with abdominal discomfort) was carried out by 150 medical doctors.
  • 96% of CNCM I-3856 consumers reported a significant improvement of gastrointestinal discomfort symptoms.
  • 64% of subjects felt a significant easing of their abdominal pain.
  • 70% of subjects also felt significantly less bloated.
  • This improvement was obtained by 77% of subjects within the first 15 days of consumption.

View Clinical Research done on Saccharomyces cerevisiae CNCM I-3856

Abdominal pain is a common symptom public health problem. Anyone can be affected by abdominal pain. In fact, you probably would have experienced this before! It is also a common complaint of school children and women with period pains. These GI disorders can disrupt everyday life. It’s physically and mentally stressful, resulting in lower productivity and quality of life.

  • Gastrointestinal (GI) disorders
    – Indigestion
    – Food poisoning
    – Constipation
    – Food allergies or intolerance
    – Trapped wind and bloating
    – Irritable bowel syndrome (IBS)
    – Overeating
    – Menstruation
    – Stomach flu
    – Anxiety or depression

The usual dose is 500mg daily with breakfast or 1000mg if required.

For children aged two years and above, you can open the capsule and mix with liquids or sprinkle over semi-solid foods.

Active Ingredients
Saccharomyces cerevisiae250mg
Capsule Sample
Pack Size
30s; 60s